|
Symbol Name ID |
Pgm3
phosphoglucomutase 3 MGI:97566 |
| Darker colors indicate more annotations |
| Human Phenotypes | Reduced antigen-specific T cell proliferation |
Increased circulating IgA level |
Increased circulating IgE level |
Increased circulating IgG level |
Increased circulating IgM level |
Bone marrow hypocellularity |
Hemolytic anemia |
Eosinophilia |
Neutropenia |
Neutropenia in presence of anti-neutropil antibodies |
Abnormal CD4:CD8 ratio |
Decreased proportion of CD4-positive helper T cells |
Abnormal proportion of CD8-positive T cells |
Decreased proportion of CD3-positive T cells |
T lymphocytopenia |
Lymphopenia |
Leukopenia |
Reduced natural killer cell count |
Lymphoma |
Hodgkin lymphoma |
| Disease(s) Associated with PGM3 | ||||||||||||||||||||
| immunodeficiency 23 |
| Mouse Phenotypes | increased spleen weight |
abnormal erythropoiesis |
increased pro-B cell number |
abnormal T cell differentiation |
abnormal thrombopoiesis |
extramedullary hematopoiesis |
anemia |
decreased bone marrow cell number |
abnormal megakaryocyte progenitor cell morphology |
decreased erythrocyte cell number |
decreased hematocrit |
thrombocytopenia |
absent follicular B cells |
decreased B cell number |
decreased T cell number |
decreased leukocyte cell number |
increased spleen red pulp amount |
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| Availability | Mouse Genotype | |||||||||||||||||
| Pgm3mld1/Pgm3mld1 | ||||||||||||||||||
| Pgm3Gt(W037B08)Wrst/Pgm3mld1 | ||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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